Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9964898 | 0.82 | NPC1 (0.48) | ACE | |
| SCHEMBL9747326 | 0.82 | NPC1 (0.48) | ACE | |
| SCHEMBL4430164 | 0.80 | MTNR1A (0.46) | NOTUMACE | |
| SCHEMBL17559463 | 0.77 | ACE (0.43) | ACE | |
| SCHEMBL19460801 | 0.77 | ACE (0.43) | ACE | |
| SCHEMBL17559367 | 0.77 | ACE (0.43) | ACE | |
| SCHEMBL19460804 | 0.77 | ACE (0.43) | ACE | |
| SCHEMBL17559368 | 0.77 | ACE (0.43) | ACE | |
| SCHEMBL4436088 | 0.77 | NOTUM (0.43) | NOTUMACE | |
| SCHEMBL4436087 | 0.77 | NOTUM (0.43) | NOTUMACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157434-A1 | Antimicrobial heterocyclic compounds for treatment of bacterial infections | CSO of MicuRx Pharmaceuticals, Inc. | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157434-A1 | Antimicrobial heterocyclic compounds for treatment of bacterial infections | NISCH, NOD1, NQO1 | NOTUM 2955/4885ACE 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.