Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 12/20 | 0.35 |
| ▸ | CALML3 | P27482 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9929978 | 0.87 | KCNH2 (0.39) | MIFKCNH2 | |
| SCHEMBL14069841 | 0.86 | MIF (0.37) | HDAC6MIFCALML3KCNH2 | |
| SCHEMBL9929910 | 0.86 | MAOB (0.34) | HDAC6MIFCALML3KCNH2 | |
| SCHEMBL9930532 | 0.85 | KCNH2 (0.45) | HDAC6MIFCALML3KCNH2 | |
| SCHEMBL9968492 | 0.84 | MIF (0.38) | HDAC6MIFCALML3KCNH2 | |
| SCHEMBL9964897 | 0.81 | MAOA (0.43) | — | |
| SCHEMBL9930570 | 0.78 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL9930700 | 0.76 | KCNH2 (0.48) | MIFCALML3KCNH2 | |
| SCHEMBL9930208 | 0.74 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL9930253 | 0.73 | KCNH2 (0.40) | HDAC6MIFCALML3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157434-A1 | Antimicrobial heterocyclic compounds for treatment of bacterial infections | CSO of MicuRx Pharmaceuticals, Inc. | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157434-A1 | Antimicrobial heterocyclic compounds for treatment of bacterial infections | NISCH, NOD1, NQO1 | HDAC6 93/4885MIF 852/4885CALML3 4013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.