Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993045 | 0.85 | CES1 (0.45) | HTTSMN1; SMN2CES1MAPTALOX15 | |
| SCHEMBL2470208 | 0.85 | EPHX1 (0.43) | HTTSMN1; SMN2CES1MAPTALOX15 | |
| SCHEMBL5677227 | 0.84 | CES2 (0.41) | HTTSMN1; SMN2CES1MAPTALOX15 | |
| SCHEMBL4959086 | 0.84 | CES1 (0.39) | HTTCES1MAPTALOX15HBB | |
| SCHEMBL7430909 | 0.82 | CES1 (0.38) | HTTCES1MAPTALOX15HBB | |
| SCHEMBL7423415 | 0.82 | CES1 (0.38) | HTTSMN1; SMN2CES1MAPTALOX15 | |
| SCHEMBL8488412 | 0.81 | CES1 (0.35) | HTTSMN1; SMN2CES1MAPTALOX15 | |
| SCHEMBL8574301 | 0.81 | TSHR (0.39) | HTTSMN1; SMN2CES1MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL8844129 | 0.81 | HTT (0.39) | HTTSMN1; SMN2CES1MAPTALOX15 | |
| SCHEMBL8486531 | 0.80 | HSD11B1 (0.35) | HTTSMN1; SMN2CES1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958280-A1 | ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1999-11-24 | — | — | EP | disclosed |
| WO-1999023072-A1 | ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1999-05-14 | — | — | WO | disclosed |