SCHEMBL7430909

SCHEMBL7430909

O=C(c1ccccc1)C1C=CC(F)(Cl)C=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.38
MAPT P10636 2/20 0.38
ALOX15 P16050 1/20 0.38
HTT P42858 1/20 0.38
HBB P68871 1/20 0.38
EPHX1 P07099 2/20 0.37
CES2 O00748 3/20 0.35
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
DAO P14920 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
POLB P06746 2/20 0.35
HSD17B10 Q99714 2/20 0.35
GAA P10253 1/20 0.35
GSK3B P49841 2/20 0.34
TRPA1 O75762 1/20 0.34
MAPK1 P28482 1/20 0.34
HIF1A Q16665 1/20 0.34
PTPN1 P18031 1/20 0.34
MCL1 Q07820 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156512 0.85 MAPT (0.40) CES1MAPTALOX15HTTHBB
SCHEMBL993045 0.85 CES1 (0.45) CES1MAPTALOX15HTTHBB
SCHEMBL4035521 0.84 ALDH1A1 (0.39) CES1MAPTALOX15HTTHBB
SCHEMBL4959086 0.84 CES1 (0.39) CES1MAPTALOX15HTTHBB
SCHEMBL7423415 0.82 CES1 (0.38) CES1MAPTALOX15HTTHBB
SCHEMBL6510160 0.82 MAPT (0.38) CES1MAPTALOX15HTTHBB
SCHEMBL7420069 0.82 HTT (0.40) CES1MAPTALOX15HTTHBB
SCHEMBL8899432 0.81 GSK3B (0.39) CES1MAPTALOX15HTTHBB
SCHEMBL136598 0.79 MAPT (0.41) CES1MAPTALOX15HTTHBB
Acetophenone SCHEMBL6800661 0.78 MAPT (0.42) CES1MAPTALOX15HTTHBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114262433-B Coupling agent and polyaryletherketone composite material prepared from coupling agent 吉林省中研高分子材料股份有限公司 2024-04-26 CN claimed
CN-115636933-B Polyaryletherketone with wide molecular weight distribution and preparation method thereof 吉林省中研高分子材料股份有限公司 2023-08-04 CN claimed
CN-115636933-A9 Polyaryletherketone with wide molecular weight distribution and preparation method thereof 吉林省中研高分子材料股份有限公司 2023-04-25 CN claimed
CN-114262433-A Coupling agent and polyaryletherketone composite material prepared from same 吉林省中研高分子材料股份有限公司 2022-04-01 CN claimed
CN-114262433-B Coupling agent and polyaryletherketone composite material prepared from coupling agent 吉林省中研高分子材料股份有限公司 2024-04-26 CN disclosed
CN-112041165-B Additive manufacturing with efficient sintering using photothermal dyes 株式会社理光 2024-01-09 CN disclosed
CN-111902456-B Copolymer and method for producing same 威格斯制造有限公司 2024-01-05 CN disclosed
CN-115636933-B Polyaryletherketone with wide molecular weight distribution and preparation method thereof 吉林省中研高分子材料股份有限公司 2023-08-04 CN disclosed
CN-115636933-A9 Polyaryletherketone with wide molecular weight distribution and preparation method thereof 吉林省中研高分子材料股份有限公司 2023-04-25 CN disclosed
CN-109843974-B Polymer and method for producing same 威格斯制造有限公司 2022-05-27 CN disclosed
CN-114262433-A Coupling agent and polyaryletherketone composite material prepared from same 吉林省中研高分子材料股份有限公司 2022-04-01 CN disclosed
CN-112041165-A Additive manufacturing using photothermal dyes for high efficiency sintering 株式会社理光 2020-12-04 CN disclosed
WO-1999023072-A1 ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME SUNTORY LIMITED (JP) 1999-05-14 WO disclosed
EP-0476106-A4 POLY(BIPHENYL ETHER SULFONE) COMPOSITIONS 1992-11-25 EP disclosed
EP-0489152-A4 THERMOPLASTIC COMPOSITIONS CONTAINING ANHYDROUS ZINC BORATE AND A FLUOROCARBON POLYMER 1992-11-25 EP disclosed
EP-0489152-A1 THERMOPLASTIC COMPOSITIONS CONTAINING ANHYDROUS ZINC BORATE AND A FLUOROCARBON POLYMER AMOCO CORPORATION (US) 1992-06-10 EP disclosed
EP-0476106-A1 POLY(BIPHENYL ETHER SULFONE) COMPOSITIONS. AMOCO CORP (US) 1992-03-25 EP disclosed
WO-1992000348-A1 THERMOPLASTIC COMPOSITIONS CONTAINING ANHYDROUS ZINC BORATE AND A FLUOROCARBON POLYMER AMOCO CORPORATION (US) 1992-01-09 WO disclosed
WO-1991015539-A1 POLY(BIPHENYL ETHER SULFONE) COMPOSITIONS AMOCO CORPORATION (US) 1991-10-17 WO disclosed
US-4963627-A INCLUDING AN INORGANIC HYDRATE AS A STABILIZER; TENSILE SRENGTH; TOUGHNESS; CURED GRAFT POLYMERS AMOCO CORPORATION (US) 1990-10-16 US disclosed