SCHEMBL993200

SCHEMBL993200

C=C(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C(=O)OCC(COC(=O)C(=C)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)(COC(=O)C(=C)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)COC(=O)C(=C)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
KMT2A Q03164 4/20 0.41
TSHR P16473 3/20 0.41
MEN1 O00255 3/20 0.41
MAPK1 P28482 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
BLM P54132 2/20 0.41
ATM Q13315 2/20 0.41
HIF1A Q16665 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
MAPT P10636 2/20 0.41
USP2 O75604 1/20 0.41
CYP2D6 P10635 1/20 0.41
GAA P10253 7/20 0.41
LMNA P02545 3/20 0.41
GMNN O75496 1/20 0.40
GABBR2 O75899 1/20 0.40
TP53 P04637 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30965767 0.93 KMT2A (0.43) ALDH1A1KMT2ATSHRMEN1MAPK1
SCHEMBL95299 0.84 GAA (0.47) ALDH1A1KMT2ATSHRMEN1MAPK1
SCHEMBL993476 0.83 HMGCR (0.38) ALDH1A1KMT2ATSHRMEN1MAPK1
SCHEMBL2351313 0.83 ALDH1A1 (0.46) ALDH1A1KMT2ATSHRMEN1MAPK1
SCHEMBL28797246 0.82 ALDH1A1 (0.43) ALDH1A1KMT2ATSHRMEN1MAPK1
SCHEMBL10399329 0.82 GAA (0.44) ALDH1A1KMT2ATSHRMEN1MAPK1
SCHEMBL10397803 0.80 GAA (0.40) ALDH1A1KMT2ATSHRMEN1MAPK1
SCHEMBL2516209 0.79 LMNA (0.45) ALDH1A1KMT2ATSHRMEN1MAPK1
SCHEMBL2674900 0.79 ALDH1A1 (0.47) ALDH1A1KMT2ATSHRMEN1MAPK1
SCHEMBL20982016 0.79 ALDH1A1 (0.51) ALDH1A1KMT2ATSHRMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117162432-A Ultra-high molecular weight polyethylene/nano filler porous membrane, preparation method and application thereof 四川大学 2023-12-05 CN claimed
CN-114051512-B Chlorinated polyvinyl chloride resin composition and chlorinated polyvinyl chloride resin molded article 积水化学工业株式会社 2024-02-13 CN disclosed
CN-117162432-A Ultra-high molecular weight polyethylene/nano filler porous membrane, preparation method and application thereof 四川大学 2023-12-05 CN disclosed
CN-110520473-B Resin composition for injection molding 积水化学工业株式会社 2022-11-04 CN disclosed
CN-110651002-B Resin composition for molding 积水化学工业株式会社 2022-06-28 CN disclosed
CN-114051512-A Chlorinated polyvinyl chloride resin composition and chlorinated polyvinyl chloride resin molded article 积水化学工业株式会社 2022-02-15 CN disclosed
US-8765850-B2 Polyacetal resin composition and preparation process thereof ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-07-01 US disclosed
EP-2267075-B1 POLYACETAL RESIN COMPOSITION AND METHOD FOR PRODUCING THE SAME ASAHI KASEI CHEMICALS CORP (JP) 2014-01-22 EP disclosed
US-20110015321-A1 POLYACETAL RESIN COMPOSITION AND PREPARATION PROCESS THEREOF ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-01-20 US disclosed
EP-2267075-A1 POLYACETAL RESIN COMPOSITION AND METHOD FOR PRODUCING THE SAME Asahi Kasei Chemicals Corporation (JP) 2010-12-29 EP disclosed
US-20090011964-A1 Lubricants Containing Multifunctional Additive Packages Therein for Improving Load-Carrying Capacity, Increasing Surface Fatigue Life and Reducing Friction UNITED TECHNOLOGIES CORPORATION 2009-01-08 US disclosed
EP-1814968-A2 LUBRICANTS CONTAINING MULTIFUNCTIONAL ADDITIVE PACKAGES THEREIN FOR IMPROVING LOAD-CARRYING CAPACITY, INCREASING SURFACE FATIGUE LIFE AND REDUCING FRICTION Pratt & Whitney (US) 2007-08-08 EP disclosed
WO-2006137928-A2 LUBRICANTS CONTAINING MULTIFUNCTIONAL ADDITIVE PACKAGES THEREIN FOR IMPROVING LOAD-CARRYING CAPACITY, INCREASING SURFACE FATIGUE LIFE AND REDUCING FRICTION UNITED TECHNOLOGIES CORPORATION (US) 2006-12-28 WO disclosed