SCHEMBL9935084

SCHEMBL9935084

CCN(CC)CCOc1ccc(CO)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.66
HTT P42858 2/20 0.66
CYP1A2 P05177 1/20 0.66
LTA4H P09960 1/20 0.66
CYP2C9 P11712 1/20 0.66
CYP2C19 P33261 1/20 0.66
EBP Q15125 3/20 0.63
SIGMAR1 Q99720 3/20 0.63
HRH3 Q9Y5N1 2/20 0.57
MCHR1 Q99705 1/20 0.53
KMT2A Q03164 3/20 0.52
KCNH2 Q12809 2/20 0.52
ESR1 P03372 2/20 0.52
CHRM2 P08172 2/20 0.52
ADRA2A P08913 2/20 0.52
ADORA3 P0DMS8 2/20 0.52
CHRM1 P11229 2/20 0.52
PTGS1 P23219 2/20 0.52
SLC6A2 P23975 2/20 0.52
SLC6A4 P31645 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706125 0.87 EBP (0.72) CYP2D6HTTCYP1A2LTA4HCYP2C9
SCHEMBL8432273 0.85 CYP1A2 (0.70) CYP2D6HTTCYP1A2LTA4HCYP2C9
SCHEMBL2424129 0.82 KEAP1 (0.69) CYP2D6HTTCYP1A2LTA4HCYP2C9
SCHEMBL15876427 0.82 CYP1A2 (0.66) CYP2D6HTTCYP1A2LTA4HCYP2C9
SCHEMBL10898516 0.82 CYP1A2 (0.66) CYP2D6HTTCYP1A2LTA4HCYP2C9
SCHEMBL6932789 0.82 CYP2D6 (0.66) CYP2D6HTTCYP1A2LTA4HCYP2C9
SCHEMBL4693255 0.81 ESR1 (0.70) CYP2D6HTTCYP1A2LTA4HCYP2C9
SCHEMBL185585 0.81 HRH3 (0.70) CYP2D6CYP1A2LTA4HEBPSIGMAR1
Hydrochloric Acid SCHEMBL1985117 0.81 CYP2D6 (0.64) CYP2D6HTTCYP1A2LTA4HCYP2C9
SCHEMBL4088440 0.80 CYP1A2 (0.59) CYP2D6HTTCYP1A2LTA4HCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012079154-A1 SELECTIVE ESTROGEN RECEPTOR MODULATORS DALHOUSIE UNIVERSITY (CA) 2012-06-21 WO disclosed