Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863399 | 0.90 | ALDH1A1 (0.59) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| SCHEMBL18651713 | 0.87 | ALDH1A1 (0.59) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| SCHEMBL12369618 | 0.85 | MAPT (0.43) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| SCHEMBL632001 | 0.83 | ALDH1A1 (0.54) | ALDH1A1LMNATDP1KMT2ATSHR | |
| SCHEMBL295552 | 0.82 | ALDH1A1 (0.57) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| SCHEMBL13120035 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| SCHEMBL9963976 | 0.81 | ALDH1A1 (0.61) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| SCHEMBL9396664 | 0.81 | KMT2A (0.56) | ALDH1A1LMNATDP1KMT2AMEN1 | |
| SCHEMBL784821 | 0.81 | ALDH1A1 (0.65) | ALDH1A1LMNATDP1ADRB2ADRB1 | |
| SCHEMBL27786896 | 0.81 | PTPN1 (0.47) | ALDH1A1LMNAADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382343-B2 | Procatalyst composition with alkoxypropyl ester internal electron donor and polymer from same | W. R. GRACE & CO.-CONN. (US) | 2016-07-05 | — | — | US | disclosed |
| US-20130289228-A1 | Procatalyst Composition with Alkoxypropyl Ester Internal Electron Donor and Polymer from Same | W. R. GRACE & CO.-CONN. | 2013-10-31 | — | — | US | disclosed |
| US-20120157645-A1 | Procatalyst Composition with Alkoxypropyl Ester Internal Electron Donor and Polymer From Same | W.R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | disclosed |
| EP-2128140-A1 | METHOD FOR PRODUCING 2-NITROIMIDAZOLE DERIVATIVE | Pola Pharma Inc. (JP) | 2009-12-02 | — | — | EP | disclosed |