Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5480554 | 0.96 | TSHR (0.60) | TSHRMEN1THRBHTTKMT2A | |
| 1,3-Propanediol SCHEMBL4332272 | 0.93 | TSHR (0.62) | TSHRMEN1THRBHTTKMT2A | |
| Di(Hydroxyethyl)Ether SCHEMBL4453213 | 0.93 | TSHR (0.77) | TSHRMEN1THRBHTTKMT2A | |
| 1,4-Butanediol SCHEMBL4318090 | 0.93 | TSHR (0.62) | TSHRMEN1THRBHTTKMT2A | |
| Butoxyethanol SCHEMBL587577 | 0.93 | TSHR (0.77) | TSHRMEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL6435690 | 0.93 | MEN1 (0.61) | TSHRMEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL9616198 | 0.93 | TSHR (0.59) | TSHRMEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL28723481 | 0.93 | TSHR (0.59) | TSHRMEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL37245 | 0.93 | TSHR (0.59) | TSHRMEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL2516099 | 0.91 | TSHR (0.74) | TSHRMEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4189 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637584-B2 | Waterborne polyurethane-epoxy resin based primer composition and its preparation method thereof | BASF COATINGS GMBH (DE) | 2026-05-26 | — | — | US | claimed |
| CN-122080768-A | Water-based high-temperature-resistant dew point corrosion-resistant coating and preparation method and construction process thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080776-A | Salt spray-resistant anti-aging cured coating and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122079799-A | Emodin modified amine curing agent, preparation method thereof, long-acting anti-corrosion coating based on body rust conversion, preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122095313-A | Light-converting curable composition, cured film comprising the same, and image display device comprising the cured film | — | 2026-05-26 | — | — | CN | claimed |
| CN-115968065-B | Electrothermal slurry and preparation method thereof | 广东骏丰频谱股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122050914-A | Low-temperature-cured non-silver-based chemically-plated flexible seed layer slurry and preparation method thereof | 苏州晶银新材料科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122037759-A | Polyurethane coating main agent, preparation method and application thereof | 卡秀(苏州)涂料有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-3503869-B1 | SUSPENSION COMPOSITIONS AND USE THEREOF FOR COUNTERACTING MALODOUR | AQDOT LTD (GB) | 2026-03-04 | — | — | EP | claimed |
| CN-121583605-A | Ultralow temperature curing conductive silver paste and element | 苏州创印电子科技有限公司 | 2026-02-27 | — | — | CN | claimed |
| US-5183514-A | Dissociation with halogen-free solvent mixtures | TEXACO CHEMICAL COMPANY (US) | 1993-02-02 | — | — | US | claimed |
| US-5160585-A | Separation of tetrachloroethylene from a butyl alcohol by extractive distillation | Berg, Lloyd (US) | 1992-11-03 | — | — | US | claimed |
| EP-0507426-A1 | Process for dissolving polyurethane foams or removing them from substrates | TEXACO CHEMICAL COMPANY (US) | 1992-10-07 | — | — | EP | claimed |
| US-5094723-A | Separation of m-xylene from p-xylene or o-xylene by extractive distillation with alcohols | Berg, Lloyd (US) | 1992-03-10 | — | — | US | claimed |
| US-5019217-A | Separation of m-xylene from o-xylene by extractive distillation using esters | Berg, Lloyd (US) | 1991-05-28 | — | — | US | claimed |
| US-4948471-A | INCREASING RELATIVE VOLATILITY | Berg, Lloyd (US) | 1990-08-14 | — | — | US | claimed |
| EP-0148698-B1 | INKS AND/OR VARNISHES FOR CARRYING OUT A METHOD FOR DECORATING A SUBSTRATE BY TRANSFERRING A PATTERN PRINTED ON A FLEXIBLE TRANSFER SHEET | Cuvelier, Georges (FR) | 1990-03-28 | — | — | EP | claimed |
| US-4840707-A | USING A DIMETHYLAMIDE | Berg, Lloyd (US) | 1989-06-20 | — | — | US | claimed |
| US-4735690-A | USING A HIGH BOILING ORGANIC COMPOUND | BERG LLOYD (US) | 1988-04-05 | — | — | US | claimed |
| US-4661209-A | USING HIGHER BOILING EXTRACTING AGENT | BERG LLOYD | 1987-04-28 | — | — | US | claimed |