Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL599482 | 0.98 | MEN1 (0.65) | MEN1THRBHTTKMT2AMAPT | |
| Acetic Acid SCHEMBL896457 | 0.98 | MEN1 (0.65) | MEN1THRBHTTKMT2AMAPT | |
| Acetic Acid SCHEMBL22445050 | 0.98 | MEN1 (0.65) | MEN1THRBHTTKMT2AMAPT | |
| Acetic Acid SCHEMBL22444982 | 0.98 | MEN1 (0.65) | MEN1THRBHTTKMT2AMAPT | |
| Acetic Acid SCHEMBL28282561 | 0.93 | MEN1 (0.72) | MEN1THRBHTTKMT2AMAPT | |
| Acetic Acid SCHEMBL99361 | 0.93 | TSHR (0.65) | MEN1THRBHTTKMT2AMAPT | |
| Acetic Acid SCHEMBL3264543 | 0.93 | CES2 (0.64) | MEN1THRBHTTKMT2AMAPT | |
| Acetic Acid SCHEMBL28282676 | 0.91 | MEN1 (0.76) | MEN1THRBHTTKMT2AMAPT | |
| Triethylene Glycol SCHEMBL19064944 | 0.91 | MEN1 (0.76) | MEN1THRBHTTKMT2AMAPT | |
| Acetic Acid SCHEMBL2863329 | 0.91 | CES2 (0.68) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11958783-B2 | Composition, film, and method for producing film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-04-16 | — | — | US | disclosed |
| WO-2020190622-A1 | POLYMER COMPOSITIONS AND USE OF THE SAME | RHODIA OPERATIONS (FR) | 2020-09-24 | — | — | WO | disclosed |
| US-10759989-B2 | Temperature-stable paraffin inhibitor compositions | ECOLAB USA INC. (US) | 2020-09-01 | — | — | US | disclosed |
| US-20200262760-A1 | Composition, Film, and Method for Producing Film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-08-20 | — | — | US | disclosed |
| EP-3686262-A1 | COMPOSITION, MEMBRANE, AND METHOD FOR PRODUCING MEMBRANE | Sumitomo Chemical Company Limited (JP) | 2020-07-29 | — | — | EP | disclosed |
| CN-111108172-A | Composition, film, and method for producing film | 住友化学株式会社 | 2020-05-05 | — | — | CN | disclosed |
| EP-3400369-A1 | TEMPERATURE-STABLE PARAFFIN INHIBITOR COMPOSITIONS | Ecolab Usa Inc. (US) | 2018-11-14 | — | — | EP | disclosed |
| WO-2017120286-A1 | TEMPERATURE-STABLE PARAFFIN INHIBITOR COMPOSITIONS | ECOLAB USA INC. (US) | 2017-07-13 | — | — | WO | disclosed |
| US-20170190949-A1 | TEMPERATURE-STABLE PARAFFIN INHIBITOR COMPOSITIONS | NORRISEAL-WELLMARK, INC. | 2017-07-06 | — | — | US | disclosed |
| US-20050044778-A1 | Fuel compositions employing catalyst combustion structure | OCTANE INTERNATIONAL, LTD. | 2005-03-03 | — | — | US | disclosed |
| US-3933518-A | CHLORINATED ALIPHATIC HYDROCARBONS, ALKYLENE GLYCOL ALKANOATE | THE DOW CHEMICAL COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933517-A | Compositions for reflowing organic surfaces | THE DOW CHEMICAL COMPANY (US) | 1976-01-20 | — | — | US | disclosed |