Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 4/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.46 |
| ▸ | DGKA | P23743 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4446355 | 0.95 | MAPT (0.64) | MAPTLMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL30970147 | 0.93 | MAPT (0.67) | MAPTLMNATSHRALDH1A1KDM4E | |
| SCHEMBL4453537 | 0.93 | MAPT (0.67) | MAPTLMNATSHRALDH1A1KDM4E | |
| SCHEMBL4456932 | 0.93 | MAPT (0.67) | MAPTLMNATSHRALDH1A1KDM4E | |
| SCHEMBL27296818 | 0.89 | MAPT (0.46) | MAPTLMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL9756884 | 0.80 | MAPT (0.63) | MAPTLMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL127789 | 0.80 | MAPT (0.63) | MAPTLMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL10403567 | 0.79 | MAPT (0.85) | MAPTLMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL21699936 | 0.77 | MAPT (0.65) | MAPTLMNATSHRALDH1A1KDM4E | |
| SCHEMBL4310169 | 0.77 | MAPT (0.59) | MAPTLMNATSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651875-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080264-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | disclosed |