SCHEMBL4446355

SCHEMBL4446355

CCCCCC(=O)OCC(C)C=O

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.64
LMNA P02545 4/20 0.57
ALDH1A1 P00352 1/20 0.57
KDM4E B2RXH2 1/20 0.56
DUSP3 P51452 1/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
DGKA P23743 2/20 0.53
TSHR P16473 2/20 0.53
CYP3A4 P08684 1/20 0.53
ATM Q13315 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
PRKCA P17252 3/20 0.53
PRKCE Q02156 1/20 0.53
PRKCQ Q04759 1/20 0.53
PRKCD Q05655 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30970147 0.98 MAPT (0.67) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL4453537 0.98 MAPT (0.67) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL4456932 0.98 MAPT (0.67) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL9936145 0.95 MAPT (0.56) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL27296818 0.87 MAPT (0.46) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL21699936 0.83 MAPT (0.65) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL11309044 0.82 LMNA (0.70) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL11306623 0.82 LMNA (0.70) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL129293 0.81 MAPT (0.72) MAPTLMNAALDH1A1KDM4EDUSP3
SCHEMBL1869509 0.81 MAPT (0.72) MAPTLMNAALDH1A1KDM4EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2132246-A1 METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT Sika Technology AG (CH) 2009-12-16 EP disclosed
WO-2008116927-A1 METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT SIKA TECHNOLOGY AG (CH) 2008-10-02 WO disclosed