Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | DGKA | P23743 | 2/20 | 0.56 |
| ▸ | PRKCA | P17252 | 3/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PAM | P19021 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456932 | 1.00 | MAPT (0.67) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL30970147 | 1.00 | MAPT (0.67) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL4446355 | 0.98 | MAPT (0.64) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL9936145 | 0.93 | MAPT (0.56) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL27296818 | 0.85 | MAPT (0.46) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL21699936 | 0.85 | MAPT (0.65) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL11306623 | 0.84 | LMNA (0.70) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL11309044 | 0.84 | LMNA (0.70) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL2397946 | 0.82 | MAPT (0.76) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL2835498 | 0.82 | MAPT (0.76) | MAPTLMNAALDH1A1KDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021391-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION WITH HIGH EARLY STRENGTH | Sika Technology AG (CH) | 2009-02-11 | — | — | EP | disclosed |
| EP-1996635-A1 | MOISTURE-CURING POLYURETHANE COMPOSITION WITH GOOD LOW-TEMPERATURE PERFORMANCE | Sika Technology AG (CH) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007128824-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION WITH HIGH EARLY STRENGTH | SIKA TECHNOLOGY AG (CH) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007104761-A1 | MOISTURE-CURING POLYURETHANE COMPOSITION WITH GOOD LOW-TEMPERATURE PERFORMANCE | SIKA TECHNOLOGY AG (CH) | 2007-09-20 | — | — | WO | disclosed |