Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760397 | 0.83 | — | — | |
| SCHEMBL8844292 | 0.78 | — | — | |
| SCHEMBL261605 | 0.78 | — | — | |
| SCHEMBL263485 | 0.74 | NPC1 (0.46) | KMT2ANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL7583994 | 0.73 | NPC1 (0.53) | KMT2ANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL2004766 | 0.73 | NPC1 (0.52) | KMT2ANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL1324 | 0.73 | NPC1 (0.62) | KMT2ANPC1RAB9ASMN1; SMN2HTT | |
| Hydrogen Sulfide SCHEMBL28438010 | 0.72 | NPC1 (0.60) | KMT2ANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL28449908 | 0.72 | NPC1 (0.60) | KMT2ANPC1RAB9ASMN1; SMN2HTT | |
| Ammonia Solution, Strong SCHEMBL16266978 | 0.72 | NPC1 (0.60) | KMT2ANPC1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081036-A2 | A PROCESS FOR PREPARATION OF 4,4'-(1-METHYL-1,2-ETHANDIYL)-BIS-(2,6-PIPERAZINEDIONE) | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-06-21 | — | — | WO | disclosed |