⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936404 | 0.83 | KMT2A (0.45) | — | |
| SCHEMBL261605 | 0.81 | — | — | |
| SCHEMBL8844292 | 0.81 | — | — | |
| SCHEMBL263485 | 0.78 | NPC1 (0.46) | — | |
| SCHEMBL5829402 | 0.77 | NPC1 (0.48) | — | |
| SCHEMBL7583994 | 0.77 | NPC1 (0.53) | — | |
| SCHEMBL262313 | 0.77 | — | — | |
| SCHEMBL1324 | 0.77 | NPC1 (0.62) | — | |
| SCHEMBL2004766 | 0.77 | NPC1 (0.52) | — | |
| SCHEMBL1491811 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186522-B2 | Using detergents to reduce artifacts during staining of biological samples; medical diagnostics and cervical cancer | CYTYC CORPORATION (US) | 2007-03-06 | — | — | US | claimed |
| US-5051417-A | Indolythiadiazines for treating heart failure | LES LABORATOIRES BEECHAM S.A. (FR) | 1991-09-24 | — | — | US | claimed |
| WO-2023179647-A1 | THERAPEUTIC VESICLES AND METHODS OF PROCESSING THE SAME | BEIJING THERAXYTE BIOSCIENCE CO., LTD. (CN) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023178500-A1 | THERAPEUTIC VESICLES AND METHODS OF PROCESSING THE SAME | BEIJING THERAXYTE BIOSCIENCE CO. LTD. (CN) | 2023-09-28 | — | — | WO | disclosed |
| CN-115536556-A | Process for producing alkylamine derivative and intermediate for producing the same | 味之素株式会社 | 2022-12-30 | — | — | CN | disclosed |
| EP-3283057-A1 | COMPOSITION AND KITS FOR PSEUDOPLASTIC MICROGEL MATRICES | Rochal Industries, LLC (US) | 2018-02-21 | — | — | EP | disclosed |
| CN-107421796-A | Solution for the tissue processing of biological sample | 罗氏血液诊断股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-103874913-B | Solution for tissue processing of biological samples | 罗氏血液诊断股份有限公司 | 2017-04-26 | — | — | CN | disclosed |
| EP-3142599-A1 | BIOMIMETIC GRAFT OR IMPLANT AND METHODS FOR PRODUCING AND USING THE SAME | The Board of Trustees of the University of Illinois (US) | 2017-03-22 | — | — | EP | disclosed |
| WO-2016168196-A1 | COMPOSITION AND KITS FOR PSEUDOPLASTIC MICROGEL MATRICES | ROCHAL INDUSTRIES, LLC (US) | 2016-10-20 | — | — | WO | disclosed |
| WO-2015175596-A1 | BIOMIMETIC GRAFT OR IMPLANT AND METHODS FOR PRODUCING AND USING THE SAME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-11-19 | — | — | WO | disclosed |
| EP-0512844-B1 | Targeted delivery of bone growth factors | CELTRIX PHARMA (US) | 1997-08-06 | — | — | EP | disclosed |
| US-5204330-A | ANTIFUNGAL COMPOUNDS | BEECHAM GROUP P.L.C. (GB) | 1993-04-20 | — | — | US | disclosed |
| WO-1992020371-A1 | TARGETED DELIVERY OF BONE GROWTH FACTORS | CELTRIX PHARMACEUTICALS, INC. (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0512844-A1 | Targeted delivery of bone growth factors | CELTRIX PHARMACEUTICALS, INC. (US) | 1992-11-11 | — | — | EP | disclosed |
| EP-0431870-A1 | Amphotericin B derivatives | Beecham Group p.l.c. (GB) | 1991-06-12 | — | — | EP | disclosed |
| US-4957905-A | ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1990-09-18 | — | — | US | disclosed |
| US-4921839-A | Erythromycin a 11,12-carbonate 9-oxime derivatives | BEECHAM GROUP P.L.C. (GB) | 1990-05-01 | — | — | US | disclosed |
| EP-0307176-A2 | Erythromycin derivatives | BEECHAM GROUP PLC (GB) | 1989-03-15 | — | — | EP | disclosed |
| EP-0284203-A2 | Erythromycin derivatives, process for their preparation and their pharmaceutical use | BEECHAM GROUP PLC (GB) | 1988-09-28 | — | — | EP | disclosed |