SCHEMBL9936532

SCHEMBL9936532

CCCCC(CC)CNCC(C)(C)C=O

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.60
ALDH1A1 P00352 4/20 0.60
CYP3A4 P08684 3/20 0.60
KDM4E B2RXH2 1/20 0.41
TDP1 Q9NUW8 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
CA2 P00918 5/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
LMNA P02545 2/20 0.35
HTT P42858 2/20 0.35
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
GLA P06280 1/20 0.35
CA1 P00915 3/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23945935 0.82 TSHR (0.69) TSHRALDH1A1CYP3A4KDM4ETDP1
SCHEMBL123557 0.77 TSHR (1.00) TSHRALDH1A1CYP3A4KDM4ETDP1
SCHEMBL14365914 0.77 TSHR (1.00) TSHRALDH1A1CYP3A4KDM4ETDP1
SCHEMBL23611735 0.77 TSHR (1.00) TSHRALDH1A1CYP3A4KDM4ETDP1
Hydrochloric Acid SCHEMBL10525132 0.75 TSHR (0.95) TSHRALDH1A1CYP3A4KDM4ETDP1
SCHEMBL24467442 0.75 TSHR (0.95) TSHRALDH1A1CYP3A4KDM4ETDP1
Fluoride SCHEMBL635215 0.75 TSHR (0.95) TSHRALDH1A1CYP3A4KDM4ETDP1
Hydrochloric Acid SCHEMBL10525129 0.75 TSHR (0.95) TSHRALDH1A1CYP3A4KDM4ETDP1
SCHEMBL28886973 0.75 TSHR (0.95) TSHRALDH1A1CYP3A4KDM4ETDP1
Hydrochloric Acid SCHEMBL2864398 0.75 TSHR (0.95) TSHRALDH1A1CYP3A4KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651876-B1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECH AG (CH) 2017-08-09 EP claimed
US-8877955-B2 Secondary aminosilanes SIKA TECHNOLOGY AG (CH) 2014-11-04 US claimed
US-20130281562-A1 SECONDARY AMINOSILANES SIKA TECHNOLOGY AG (CH) 2013-10-24 US claimed
EP-2651876-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS Sika Technology AG (CH) 2013-10-23 EP claimed
US-20130261270-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2013-10-03 US claimed
EP-2468759-A1 Secondary Aminosilanes Sika Technology AG (CH) 2012-06-27 EP claimed
WO-2012080265-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2012-06-21 WO claimed
EP-2465843-A1 Polyamines with secondary aliphatic amines Sika Technology AG (CH) 2012-06-20 EP claimed
EP-3484898-B1 METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE MOMENTIVE PERFORMANCE MAT INC (US) 2023-06-28 EP disclosed
EP-4053134-A1 METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE Momentive Performance Materials Inc. (US) 2022-09-07 EP disclosed
US-11230563-B2 Method of stabilizing imino-functional silane MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-01-25 US disclosed
US-10457697-B2 Method of stabilizing imino-functional silane MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-10-29 US disclosed
US-20180016287-A1 METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE MOMENTIVE PERFORMANCE MATERIALS INC. 2018-01-18 US disclosed
EP-2651876-B1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECH AG (CH) 2017-08-09 EP disclosed
EP-2651956-A1 SECONDARY AMINOSILANES Sika Technology AG (CH) 2013-10-23 EP disclosed
US-20130261270-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2013-10-03 US disclosed
EP-2468759-A1 Secondary Aminosilanes Sika Technology AG (CH) 2012-06-27 EP disclosed
WO-2012080266-A1 SECONDARY AMINOSILANES SIKA TECHNOLOGY AG (CH) 2012-06-21 WO disclosed
WO-2012080265-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2012-06-21 WO disclosed
EP-2465843-A1 Polyamines with secondary aliphatic amines Sika Technology AG (CH) 2012-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11230563-B2 Method of stabilizing imino-functional silane INF2, RNF168, BOLA2; BOLA2B TSHR 4032/4885ALDH1A1 1467/4885CYP3A4 3692/4885
US-20130281562-A1 SECONDARY AMINOSILANES AS3MT, SRM, MSN TSHR 4730/4885ALDH1A1 1639/4885CYP3A4 4411/4885
US-10457697-B2 Method of stabilizing imino-functional silane INF2, RNF168, BOLA2; BOLA2B TSHR 4032/4885ALDH1A1 1467/4885CYP3A4 3692/4885
US-20180016287-A1 METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE INF2, RNF168, BOLA2; BOLA2B TSHR 4032/4885ALDH1A1 1467/4885CYP3A4 3692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.