Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446777 | 0.87 | ALDH1A1 (0.68) | NR4A2ALDH1A1HPGDKDM4EMTNR1A | |
| SCHEMBL3566514 | 0.87 | ALDH1A1 (0.83) | NR4A2ALDH1A1HPGDKDM4EMTNR1A | |
| SCHEMBL6029339 | 0.85 | ALDH1A1 (0.62) | NR4A2ALDH1A1HPGDKDM4EMTNR1A | |
| SCHEMBL14410811 | 0.84 | ALDH1A1 (0.65) | NR4A2ALDH1A1HPGDKDM4EMTNR1A | |
| SCHEMBL2034797 | 0.84 | NR4A2 (0.62) | NR4A2ALDH1A1HPGDKDM4ECREBBP | |
| SCHEMBL2036909 | 0.83 | NR4A2 (1.00) | NR4A2ALDH1A1HPGDKDM4ECREBBP | |
| SCHEMBL27436908 | 0.82 | ALDH1A1 (0.65) | NR4A2ALDH1A1HPGDKDM4EMTNR1A | |
| SCHEMBL2040417 | 0.81 | NR4A2 (1.00) | NR4A2ALDH1A1HPGDKDM4ECREBBP | |
| SCHEMBL2034149 | 0.81 | NR4A2 (0.70) | NR4A2ALDH1A1HPGDKDM4ECREBBP | |
| SCHEMBL17113293 | 0.81 | NR4A2 (0.70) | NR4A2ALDH1A1HPGDKDM4ECREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993523-B2 | Dimeric IAP inhibitors | NOVARTIS AG (CH) | 2015-03-31 | — | — | US | disclosed |
| US-20130309247-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2013-11-21 | — | — | US | disclosed |
| EP-2651919-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080271-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| WO-2010008727-A1 | ASYMMETRIC SYNTHESIS OF ALLYL OR ALLENE OXINDOLES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130309247-A1 | DIMERIC IAP INHIBITORS | XIAP, BIRC5, BIRC2 | NR4A2 3995/4885ALDH1A1 4204/4885HPGD 3794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.