Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14832743 | 0.94 | SNCA (0.47) | SNCAPRKDCESR1ESR2NPSR1 | |
| SCHEMBL14832844 | 0.92 | SNCA (0.46) | SNCAPRKDCESR1ESR2NPSR1 | |
| SCHEMBL14832718 | 0.84 | PRKDC (0.40) | SNCAPRKDCNPSR1MAPK1KDM4E | |
| SCHEMBL14838439 | 0.83 | SNCA (0.41) | SNCAKDM4ENPC1KIF11TP53 | |
| SCHEMBL14832847 | 0.83 | SNCA (0.41) | SNCAPRKDCNPSR1MAPK1KDM4E | |
| SCHEMBL16024135 | 0.82 | SNCA (0.53) | SNCAESR1ESR2KIF11 | |
| SCHEMBL23448488 | 0.79 | SNCA (0.53) | SNCAESR1ESR2NPSR1MAPK1 | |
| SCHEMBL16021757 | 0.79 | SNCA (0.46) | SNCAESR1ESR2KIF11JAK2 | |
| SCHEMBL3597485 | 0.76 | SNCA (0.53) | SNCAESR1ESR2KDM4ENPC1 | |
| SCHEMBL14832796 | 0.76 | SNCA (0.53) | SNCAPRKDCESR1ESR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230046046-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-02-16 | — | — | US | disclosed |
| CN-108690045-B | Diarylethene compounds and uses thereof | 首诺加拿大公司 | 2022-08-30 | — | — | CN | disclosed |
| US-11124524-B2 | Diarylethene compounds and uses thereof | SOLUTIA CANADA INC. (US) | 2021-09-21 | — | — | US | disclosed |
| WO-2021104749-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-06-03 | — | — | WO | disclosed |
| US-10556912-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2020-02-11 | — | — | US | disclosed |
| EP-2652547-B1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO- PLANAR ELECTRODE SYSTEM | SWITCH MAT INC (CA) | 2019-10-23 | — | — | EP | disclosed |
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2019-08-22 | — | — | US | disclosed |
| US-10254616-B2 | Variable transmittance optical filter with substantially co-planar electrode system | SWITCH MATERIALS, INC. (CA) | 2019-04-09 | — | — | US | disclosed |
| US-20180339995-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2018-11-29 | — | — | US | disclosed |
| US-10139695-B2 | Variable transmittance optical devices | SWITCH MATERIALS, INC. (CA) | 2018-11-27 | — | — | US | disclosed |
| US-20130278989-A1 | VARIABLE TRANSMITTANCE OPTICAL DEVICES | SWITCH MATERIALS, INC. (CA) | 2013-10-24 | — | — | US | disclosed |
| US-20130278989-A1 | VARIABLE TRANSMITTANCE OPTICAL DEVICES | SWITCH MATERIALS, INC. (CA) | 2013-10-24 | — | — | US | disclosed |
| US-20130278989-A1 | VARIABLE TRANSMITTANCE OPTICAL DEVICES | SWITCH MATERIALS, INC. (CA) | 2013-10-24 | — | — | US | disclosed |
| EP-2652547-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO- PLANAR ELECTRODE SYSTEM | Switch Materials, Inc. (CA) | 2013-10-23 | — | — | EP | disclosed |
| US-20130271811-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO-PLANAR ELECTRODE SYSTEM | SWITCH MATERIALS, INC. (CA) | 2013-10-17 | — | — | US | disclosed |
| US-20130271811-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO-PLANAR ELECTRODE SYSTEM | SWITCH MATERIALS, INC. (CA) | 2013-10-17 | — | — | US | disclosed |
| US-20130271811-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO-PLANAR ELECTRODE SYSTEM | SWITCH MATERIALS, INC. (CA) | 2013-10-17 | — | — | US | disclosed |
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
| WO-2012079160-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER WITH SUBSTANTIALLY CO- PLANAR ELECTRODE SYSTEM | SWITCH MATERIALS, INC. (CA) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | SNCA 3283/4885PRKDC 1839/4885ESR1 1818/4885 |
| US-10556912-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | SNCA 3283/4885PRKDC 1839/4885ESR1 1818/4885 |
| US-10254616-B2 | Variable transmittance optical filter with substantially co-planar electrode system | HCN2, HCN4, HCN1 | SNCA 428/4885PRKDC 488/4885ESR1 867/4885 |
| US-20230046046-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, CYP2C19, ESR1 | SNCA 610/4885PRKDC 1935/4885ESR1 3/4885 |
| US-11124524-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | SNCA 3283/4885PRKDC 1839/4885ESR1 1818/4885 |
| US-20180339995-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | HCN2, KCNH2, KCNH3 | SNCA 3042/4885PRKDC 1710/4885ESR1 1858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.