Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143514 | 0.87 | VCAM1 (0.66) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL9793498 | 0.87 | PTPN11 (0.49) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL1800085 | 0.86 | VCAM1 (0.60) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL28326042 | 0.84 | VCAM1 (0.62) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL16953617 | 0.83 | VCAM1 (0.60) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL11689602 | 0.80 | TSHR (0.50) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL11477482 | 0.78 | VCAM1 (0.68) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL82629 | 0.77 | VCAM1 (0.66) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL404745 | 0.75 | VCAM1 (0.64) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL1343562 | 0.75 | VCAM1 (1.00) | VCAM1MAPTGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651921-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| US-20130253011-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-09-26 | — | — | US | disclosed |
| US-20130253011-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-09-26 | — | — | US | disclosed |
| CN-103261188-A | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG | 2013-08-21 | — | — | CN | disclosed |
| WO-2012080376-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080376-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253011-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | VCAM1 4696/4885MAPT 3562/4885GRIA1 3993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.