SCHEMBL9937175

SCHEMBL9937175

C#Cc1c2ccccc2cc2cccc(-c3csc(-c4cccs4)c3-c3cccc4cc5ccccc5c(C#C)c34)c12

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.36
CES1 P23141 1/20 0.34
NQO2 P16083 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
RPS6KB2 Q9UBS0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9936961 0.85 PABPC1 (0.39) PIM1CES1ALDH1A1HPGDTSHR
SCHEMBL9937173 0.78 PABPC1 (0.43) PIM1CES1NQO2ALDH1A1HPGD
SCHEMBL9936772 0.72 CES1 (0.39) PIM1CES1NQO2ALDH1A1HPGD
SCHEMBL186912 0.72 CES1 (0.42) CES1NQO2ALDH1A1HPGDTSHR
SCHEMBL29663912 0.72 CES1 (0.42) CES1NQO2ALDH1A1HPGDTSHR
SCHEMBL19742067 0.71 KDM4E (0.39) ALDH1A1HPGDTSHRMAPK1HSD17B10
SCHEMBL2389040 0.70 CES1 (0.41) CES1NQO2ALDH1A1HPGDTSHR
SCHEMBL20657064 0.70 CES1 (0.41) CES1ALDH1A1HPGDTSHRMAPK1
Anthracene SCHEMBL28247073 0.70 CES1 (0.41) PIM1CES1NQO2ALDH1A1HPGD
SCHEMBL29726009 0.66 ALDH1A1 (0.40) PIM1NQO2ALDH1A1HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2675800-A1 FUNCTIONALIZED ANTHRACENE-CAPPED OLIGOTHIOPHENES AND ORGANIC SEMICONDUCTORS BASED ON THE SAME, USE THEREOF Institute Of Chemistry, Chinese Academy Of Sciences (CN) 2013-12-25 EP disclosed
WO-2012079545-A1 FUNCTIONALIZED ANTHRACENE-CAPPED OLIGOTHIOPHENES AND ORGANIC SEMICONDUCTORS BASED ON THE SAME, USE THEREOF CHINESE ACADEMY OF SCIENCE INSTITUTE OF CHEMISTRY (CN) 2012-06-21 WO disclosed