Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 18/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9935277 | 0.84 | DGAT1 (0.53) | DGAT1 | |
| SCHEMBL9936821 | 0.78 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL9936134 | 0.78 | DGAT1 (0.53) | DGAT1 | |
| SCHEMBL9936570 | 0.77 | DGAT1 (0.61) | DGAT1 | |
| SCHEMBL9936647 | 0.76 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL9935292 | 0.76 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL9936636 | 0.75 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL9936721 | 0.74 | DGAT1 (0.67) | DGAT1HSD17B1HSD17B2 | |
| SCHEMBL9937472 | 0.73 | DGAT1 (0.36) | DGAT1HSD17B1HSD17B2 | |
| SCHEMBL9935598 | 0.70 | DGAT1 (0.54) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651915-A1 | CONTINUOUS ARYCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012081736-A1 | CONTINUOUS ARYCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-06-21 | — | — | WO | disclosed |