Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 8/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9935278 | 0.83 | DGAT1 (0.49) | DGAT1 | |
| SCHEMBL9936826 | 0.79 | DGAT1 (0.55) | DGAT1 | |
| SCHEMBL9936135 | 0.78 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL9936572 | 0.78 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL9936649 | 0.77 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL9935296 | 0.77 | DGAT1 (0.47) | DGAT1 | |
| SCHEMBL9936638 | 0.76 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL9937470 | 0.73 | DGAT1 (0.40) | DGAT1HSD17B1HSD17B2 | |
| SCHEMBL9935600 | 0.70 | DGAT1 (0.49) | DGAT1 | |
| SCHEMBL9936721 | 0.69 | DGAT1 (0.67) | DGAT1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651915-A1 | CONTINUOUS ARYCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012081736-A1 | CONTINUOUS ARYCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-06-21 | — | — | WO | disclosed |