Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 1-Methylimidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | QPCT | Q16769 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Methylimidazole SCHEMBL15295407 | 0.88 | NFKB1 (0.60) | NFKB1QPCTHSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL27681651 | 0.88 | NFKB1 (0.60) | NFKB1QPCTHSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL28257518 | 0.88 | NFKB1 (0.60) | NFKB1QPCTHSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL693786 | 0.87 | NFKB1 (0.71) | NFKB1QPCTHSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL4955404 | 0.87 | NFKB1 (0.71) | NFKB1QPCTHSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL27681653 | 0.87 | NFKB1 (0.71) | NFKB1QPCTHSD17B10QPCTLHTT | |
| Sulfuric Acid Dimethyl Ester SCHEMBL28773173 | 0.86 | HSD17B10 (0.62) | NFKB1QPCTHSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL27724089 | 0.85 | NFKB1 (0.68) | NFKB1QPCTHSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL28194536 | 0.85 | QPCT (0.68) | NFKB1QPCTHSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL459534 | 0.85 | QPCT (0.68) | NFKB1QPCTHSD17B10QPCTLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240133117-A1 | DYE RECYCLING METHODS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2024-04-25 | — | — | US | claimed |
| EP-4294977-A1 | DYE RECYCLING METHODS | Imperial College Innovations Limited (GB) | 2023-12-27 | — | — | EP | claimed |
| CN-116917568-A | Method for recovering dye | 帝国理工学院创新有限公司 | 2023-10-20 | — | — | CN | claimed |
| WO-2022175559-A1 | DYE RECYCLING METHODS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2022-08-25 | — | — | WO | claimed |
| CN-106694007-B | A kind of single dispersion metal atom/graphene composite catalyst and its preparation method and application | 中国科学院山西煤炭化学研究所 | 2019-09-10 | — | — | CN | claimed |
| CN-106654300-B | A kind of electrochemistry swelling graphite prepares single dispersion metal atom/graphene composite material method | 中国科学院山西煤炭化学研究所 | 2019-06-25 | — | — | CN | claimed |
| CN-109504015-A | Electrochromic polymeric compounds material based on combined strategy and prepare electrochromic device | 常州铱视光电科技有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-109311903-A | Cyclic annular 3- phenyl tetramic acid derivatives with herbicide effect | 拜耳作物科学股份公司 | 2019-02-05 | — | — | CN | claimed |
| CN-109288500-A | Wearable garment sensor and preparation method and application thereof | 南方科技大学 | 2019-02-01 | — | — | CN | claimed |
| CN-109280186-A | For solidifying the method and composition on the surface of uncured polysulfide rubber | 波音公司 | 2019-01-29 | — | — | CN | claimed |
| CN-103773054-A | Preparation method of wood fiber bio-based plastic | UNIV NANJING FORESTRY | 2014-05-07 | — | — | CN | claimed |
| CN-103627254-A | Ceramic ink-jet printing used yellow glaze printing ink for ceramic ink-jet printing and preparation method thereof | JIANGXI JINXIU MODERN CHEMICAL CO LTD | 2014-03-12 | — | — | CN | claimed |
| CN-103242903-A | Method for desulfurizing fuel | ZHENG SHUNSHENG | 2013-08-14 | — | — | CN | claimed |
| CN-103228607-A | Method for synthesizing lactic acid and alkyl lactate from carbohydrate-containing raw materials | MICROVAST INC | 2013-07-31 | — | — | CN | claimed |
| CN-103189466-A | Working medium for absorption heat pumps | EVONIK DEGUSSA GMBH | 2013-07-03 | — | — | CN | claimed |
| CN-102924204-A | Method for degrading and preparing micromolecule phenolic compound in ionic liquid by using microwave strengthened lignin | UNIV ZHEJIANG | 2013-02-13 | — | — | CN | claimed |
| CN-102174620-A | Method for synthesizing salidroside by utilizing enzyme catalyzed direct glucosylation | UNIV FUZHOU | 2011-09-07 | — | — | CN | claimed |
| US-20110000823-A1 | MEMBRANE DESULFURIZATION OF LIQUID HYDROCARBONS USING AN EXTRACTIVE LIQUID MEMBRANE CONTACTOR SYSTEM AND METHOD | SAUDI ARABIAN OIL COMPANY (SA) | 2011-01-06 | — | — | US | claimed |
| CN-101679245-A | The tetramates hydrochlorate that 3-(2-alkoxyl phenyl) replaces | BAYER CROPSCIENCE AG | 2010-03-24 | — | — | CN | claimed |
| CN-101456813-A | Method for synthesizing polyatomic alcohol fatty acid ester | LANZHOU CHEM PHYS INST (CN) | 2009-06-17 | — | — | CN | claimed |