Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of 1-Methylimidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Methylimidazole SCHEMBL28194536 | 1.00 | QPCT (0.68) | QPCTNFKB1HSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL29110568 | 0.98 | NFKB1 (0.65) | QPCTNFKB1HSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL15295407 | 0.94 | NFKB1 (0.60) | QPCTNFKB1HSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL693786 | 0.93 | NFKB1 (0.71) | QPCTNFKB1HSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL4955404 | 0.93 | NFKB1 (0.71) | QPCTNFKB1HSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL27681653 | 0.93 | NFKB1 (0.71) | QPCTNFKB1HSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL27724089 | 0.91 | NFKB1 (0.68) | QPCTNFKB1HSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL27993647 | 0.91 | NFKB1 (0.68) | QPCTNFKB1HSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL28175971 | 0.89 | NFKB1 (0.65) | QPCTNFKB1HSD17B10QPCTLHTT | |
| 1-Methylimidazole SCHEMBL28339216 | 0.89 | NFKB1 (0.65) | QPCTNFKB1HSD17B10QPCTLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240133117-A1 | DYE RECYCLING METHODS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2024-04-25 | — | — | US | claimed |
| WO-2023247987-A1 | IONIC LIQUID ENCAPSULATED METAL ORGANIC FRAMEWORK BASED THIN FILM NANOCOMPOSITE MEMBRANE FOR METAL IONS SEPARATION | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2023-12-28 | — | — | WO | claimed |
| EP-4294977-A1 | DYE RECYCLING METHODS | Imperial College Innovations Limited (GB) | 2023-12-27 | — | — | EP | claimed |
| CN-116917568-A | Method for recovering dye | 帝国理工学院创新有限公司 | 2023-10-20 | — | — | CN | claimed |
| WO-2022175559-A1 | DYE RECYCLING METHODS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2022-08-25 | — | — | WO | claimed |
| EP-3512905-B1 | METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) | BASF SE (DE) | 2022-08-24 | — | — | EP | claimed |
| CN-109790292-B | Process for preparing polybenzazole polymer (P) | 巴斯夫欧洲公司 | 2022-05-31 | — | — | CN | claimed |
| CN-106694007-B | A kind of single dispersion metal atom/graphene composite catalyst and its preparation method and application | 中国科学院山西煤炭化学研究所 | 2019-09-10 | — | — | CN | claimed |
| EP-3512905-A1 | METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) | BASF SE (DE) | 2019-07-24 | — | — | EP | claimed |
| CN-110041631-A | A kind of wear-resistant plastic of modification and preparation method thereof | 王德秀 | 2019-07-23 | — | — | CN | claimed |
| US-7659430-B2 | Method for separating hydrogen chloride and phosgene | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-09 | — | — | US | claimed |
| EP-1789160-B1 | METHOD FOR SEPARATING HYDROGEN CHLORIDE AND PHOSGENE | BASF SE (DE) | 2009-11-18 | — | — | EP | claimed |
| CN-100430356-C | Method for producing haloalkanes from alcohols | BASF AG (DE) | 2008-11-05 | — | — | CN | claimed |
| WO-2008022983-A2 | CONDUCTIVE POLYMER GELS | BASF SE (DE) | 2008-02-28 | — | — | WO | claimed |
| US-20070293707-A1 | Method for Separating Hydrogen Chloride and Phosgene | BASF AKTIENGESELLSCHAFT (DE) | 2007-12-20 | — | — | US | claimed |
| EP-1789160-A1 | METHOD FOR SEPARATING HYDROGEN CHLORIDE AND PHOSGENE | BASF AKTIENGESELLSCHAFT (DE) | 2007-05-30 | — | — | EP | claimed |
| EP-1663921-B1 | METHOD FOR PRODUCING HALOALKANES FROM ALCOHOLS | BASF AG (DE) | 2007-05-02 | — | — | EP | claimed |
| US-20070055084-A1 | Method for producing haloalkanes from alcohols | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-08 | — | — | US | claimed |
| CN-1849281-A | Method for producing haloalkanes from alcohols | BASF AG (DE) | 2006-10-18 | — | — | CN | claimed |
| WO-2006029788-A1 | METHOD FOR SEPARATING HYDROGEN CHLORIDE AND PHOSGENE | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293707-A1 | Method for Separating Hydrogen Chloride and Phosgene | PSPH, SLC9B2, HVCN1 | QPCT 1147/4885NFKB1 4377/4885HSD17B10 142/4885 |
| US-20070055084-A1 | Method for producing haloalkanes from alcohols | ADH1C, HDHD5, ADH5 | QPCT 510/4885NFKB1 2976/4885HSD17B10 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.