Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK1 | P19367 | 11/20 | 0.52 |
| ▸ | HK2 | P52789 | 11/20 | 0.52 |
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9937695 | 0.86 | HK1 (0.69) | HK1HK2GCKEPHX2LMNA | |
| SCHEMBL9937688 | 0.86 | HK1 (0.69) | HK1HK2GCKEPHX2LMNA | |
| SCHEMBL9938503 | 0.85 | HK1 (0.57) | HK1HK2GCKLGALS3 | |
| SCHEMBL9938663 | 0.84 | HK1 (0.73) | HK1HK2GCK | |
| SCHEMBL9938280 | 0.79 | HK2 (0.76) | HK1HK2GCK | |
| SCHEMBL9937795 | 0.77 | HK1 (0.49) | HK1HK2GCK | |
| SCHEMBL9971331 | 0.74 | HK1 (0.73) | HK1HK2GCK | |
| SCHEMBL9971335 | 0.69 | HK1 (0.40) | HK1HK2GCKEPHX2LMNA | |
| SCHEMBL9938774 | 0.68 | HK1 (0.60) | HK1HK2GCKEPHX2NR1H4 | |
| SCHEMBL9938769 | 0.68 | HK1 (0.60) | HK1HK2GCKEPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083145-A1 | GLUCOSAMINE DERIVATIVES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-06-21 | — | — | WO | disclosed |