Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK2 | P52789 | 17/20 | 0.75 |
| ▸ | HK1 | P19367 | 16/20 | 0.75 |
| ▸ | GCK | P35557 | 1/20 | 0.75 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938660 | 0.88 | HK1 (0.72) | HK2HK1GCK | |
| SCHEMBL9938755 | 0.83 | HK2 (0.51) | HK2HK1GCK | |
| SCHEMBL9938496 | 0.81 | HK1 (0.56) | HK2HK1GCK | |
| SCHEMBL9938498 | 0.81 | HK1 (0.56) | HK2HK1GCK | |
| SCHEMBL9938280 | 0.79 | HK2 (0.76) | HK2HK1GCKITGAV | |
| SCHEMBL9937795 | 0.78 | HK1 (0.49) | HK2HK1GCK | |
| SCHEMBL9937930 | 0.76 | HK1 (0.46) | HK2HK1GCK | |
| SCHEMBL9938812 | 0.75 | HK1 (0.62) | HK2HK1GCK | |
| SCHEMBL9938814 | 0.75 | HK1 (0.62) | HK2HK1GCK | |
| SCHEMBL9971310 | 0.74 | HK1 (0.56) | HK2HK1GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083145-A1 | GLUCOSAMINE DERIVATIVES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-06-21 | — | — | WO | disclosed |