Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK2 | P52789 | 15/20 | 0.51 |
| ▸ | HK1 | P19367 | 14/20 | 0.51 |
| ▸ | GCK | P35557 | 1/20 | 0.49 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9971377 | 0.85 | HK2 (0.39) | HK2HK1GCKHSD11B1 | |
| SCHEMBL9938276 | 0.83 | HK2 (0.75) | HK2HK1GCK | |
| SCHEMBL9938761 | 0.79 | HK2 (0.51) | HK2HK1GCKHSD11B1 | |
| SCHEMBL9938660 | 0.69 | HK1 (0.72) | HK2HK1GCKCA1CA2 | |
| SCHEMBL9971339 | 0.68 | HK2 (0.63) | HK2HK1GCK | |
| SCHEMBL10871708 | 0.65 | PYGB (0.50) | CA1CA2CA9 | |
| SCHEMBL6127768 | 0.63 | MAPK1 (0.48) | — | |
| SCHEMBL10960278 | 0.62 | MAPK1 (0.59) | CA1CA2CA9 | |
| SCHEMBL10960274 | 0.62 | MAPK1 (0.59) | CA1CA2CA9 | |
| SCHEMBL11302596 | 0.60 | LGALS8 (0.46) | HK2HK1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083145-A1 | GLUCOSAMINE DERIVATIVES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-06-21 | — | — | WO | disclosed |