Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK1 | P19367 | 8/20 | 0.46 |
| ▸ | HK2 | P52789 | 8/20 | 0.46 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CD22 | P20273 | 2/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9971381 | 0.87 | ALDH1A1 (0.41) | HK1HK2KDM4EALDH1A1HPGD | |
| SCHEMBL9938774 | 0.87 | HK1 (0.60) | HK1HK2GCKKDM4EALDH1A1 | |
| SCHEMBL9938769 | 0.87 | HK1 (0.60) | HK1HK2GCKKDM4EALDH1A1 | |
| SCHEMBL9937795 | 0.82 | HK1 (0.49) | HK1HK2GCK | |
| SCHEMBL9938496 | 0.80 | HK1 (0.56) | HK1HK2GCK | |
| SCHEMBL9938498 | 0.80 | HK1 (0.56) | HK1HK2GCK | |
| SCHEMBL9938660 | 0.80 | HK1 (0.72) | HK1HK2GCK | |
| SCHEMBL9938276 | 0.76 | HK2 (0.75) | HK1HK2GCK | |
| SCHEMBL1926645 | 0.71 | NPC1 (0.78) | KDM4EALDH1A1HPGDSMN1; SMN2ERN1 | |
| SCHEMBL9938990 | 0.71 | HK1 (0.74) | HK1HK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083145-A1 | GLUCOSAMINE DERIVATIVES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-06-21 | — | — | WO | disclosed |