Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466437 | 0.90 | ADORA3 (0.50) | KDM4EPKMHSP90AA1HSP90AB1CYP2D6 | |
| SCHEMBL9939645 | 0.90 | KDM4E (0.44) | KDM4EPKMHSP90AA1HSP90AB1CYP1A2 | |
| SCHEMBL27922410 | 0.88 | JAK2 (0.39) | KDM4EPKMCYP1A2CYP2C9RCE1 | |
| SCHEMBL9939442 | 0.87 | ABL1 (0.48) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9939529 | 0.86 | KDM4E (0.40) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9939395 | 0.85 | KDM4E (0.39) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2467009 | 0.85 | KDM4E (0.52) | KDM4EPKMCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9939744 | 0.83 | ALDH1A1 (0.43) | KDM4EPKMHSP90AA1HSP90AB1CYP1A2 | |
| SCHEMBL9937674 | 0.83 | HTT (0.42) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9939089 | 0.82 | CFTR (0.49) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665710-A1 | 6-(2-AMINOPHENYL)PICOLINATES AND THEIR USE AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2013-11-27 | — | — | EP | disclosed |
| WO-2012080187-A1 | 6-(2-AMINOPHENYL)PICOLINATES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-21 | — | — | WO | disclosed |