Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | AOC2 | O75106 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132372 | 0.99 | HDAC3 (0.53) | HDAC3HDAC8SMYD3HDAC6AOC2 | |
| SCHEMBL6232666 | 0.85 | USP2 (0.55) | HDAC3HDAC8CHRM4HTR2AHTR2C | |
| SCHEMBL6234622 | 0.83 | HDAC3 (0.57) | HDAC3HDAC8CHRM4 | |
| SCHEMBL3085835 | 0.82 | AOC2 (0.59) | HDAC3HDAC8SMYD3HDAC6AOC2 | |
| SCHEMBL6132264 | 0.82 | HDAC3 (0.56) | HDAC3HDAC8CHRM4 | |
| SCHEMBL3107802 | 0.81 | CASP1 (0.41) | HDAC6CHRM4 | |
| SCHEMBL6134717 | 0.81 | ITGB3 (0.52) | HDAC3HDAC8SMYD3HDAC6KDM4E | |
| SCHEMBL6134192 | 0.80 | ITGB3 (0.51) | HDAC3HDAC8SMYD3HDAC6KDM4E | |
| SCHEMBL30476653 | 0.79 | HDAC6 (0.71) | SMYD3HDAC6AOC2KDM4E | |
| SCHEMBL6369562 | 0.78 | ALDH1A1 (0.53) | HDAC3HDAC8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009632-A2 | METHODS FOR FORMING TUNABLE MOLECULAR GRADIENTS ON SUBSTRATES | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-02-03 | — | — | WO | disclosed |
| WO-2005005463-A1 | ANTIFUNGAL CYCLIC LIPOPEPTIDES | ASTELLAS PHARMA INC. (JP) | 2005-01-20 | — | — | WO | disclosed |
| US-20050014685-A1 | New compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| US-6770323-B2 | REACTING A COMPONENT WITH A SUBSTRATE SURFACE TO FORM A FIRST DISTRIBUTION OF THE COMPONENT ON THE SURFACE; AND DEFORMING THE SURFACE ALONG ON AXIS SO THE FIRST DISTRIBUTION IS CONVERTED TO A SECOND DISTRIBUTION THAT IS A GRADIENT | NORTH CAROLINA STATE UNIVERSITY | 2004-08-03 | — | — | US | disclosed |
| US-20030015495-A1 | Methods for forming tunable molecular gradients on substrates | NORTH CAROLINA STATE UNIVERSITY | 2003-01-23 | — | — | US | disclosed |
| US-20020106449-A1 | TAILORING THE GRAFTING DENSITY OF ORGANIC MODIFIERS AT SOLID/LIQUID INTERFACES | NORTH CAROLINA STATE UNIVERSITY | 2002-08-08 | — | — | US | disclosed |
| US-6423372-B1 | SURFACE TREATMENT OF ELASTIC SUBSTRATES, STRETCHING AND RELEASING | NORTH CAROLINA STATE UNIVERSITY | 2002-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014685-A1 | New compound | MAN2B1, MAN2A1, MANBA | HDAC3 1497/4885HDAC8 1977/4885SMYD3 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.