Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055956 | 0.81 | KDM4E (0.67) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3953775 | 0.79 | KDM4E (0.59) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3953773 | 0.79 | KDM4E (0.59) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9935084 | 0.78 | CYP2D6 (0.66) | KDM4EKMT2AMEN1CYP1A2LTA4H | |
| SCHEMBL29334676 | 0.78 | KDM4E (0.48) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9292741 | 0.78 | ALDH1A1 (0.49) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5176969 | 0.77 | KDM4E (0.65) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL219418 | 0.77 | KDM4E (0.60) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11649743 | 0.74 | HRH3 (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1LTA4H | |
| SCHEMBL185585 | 0.74 | HRH3 (0.70) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |