Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | LTA4H | P09960 | 8/20 | 0.57 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.55 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | GCGR | P47871 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9942715 | 1.00 | ESR1 (0.57) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL9967008 | 0.99 | LTA4H (0.56) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL9940088 | 0.95 | LTA4H (0.56) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL9940306 | 0.95 | LTA4H (0.56) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL9966732 | 0.94 | LTA4H (0.55) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL9966789 | 0.94 | LTA4H (0.55) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL9966961 | 0.94 | LTA4H (0.55) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL9966735 | 0.93 | LTA4H (0.54) | ESR1ESR2LTA4HPSMB1PSMB5 | |
| SCHEMBL9967005 | 0.91 | LTA4H (0.58) | ESR1ESR2LTA4HOPRK1GCGR | |
| SCHEMBL9967009 | 0.90 | LTA4H (0.58) | ESR1ESR2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |