Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966973 | 0.95 | LTA4H (0.57) | LTA4HESR1ESR2MEN1KMT2A | |
| SCHEMBL9966793 | 0.94 | LTA4H (0.56) | LTA4HESR1ESR2MEN1KMT2A | |
| SCHEMBL9967008 | 0.92 | LTA4H (0.56) | LTA4HESR1ESR2HRH3OPRK1 | |
| SCHEMBL9942715 | 0.91 | ESR1 (0.57) | LTA4HESR1ESR2HRH3OPRK1 | |
| SCHEMBL9940337 | 0.91 | ESR1 (0.57) | LTA4HESR1ESR2HRH3OPRK1 | |
| SCHEMBL9967004 | 0.89 | LTA4H (0.50) | LTA4HESR1ESR2HRH3OPRK1 | |
| SCHEMBL9967009 | 0.89 | LTA4H (0.58) | LTA4HESR1ESR2NPC1RAB9A | |
| SCHEMBL9966797 | 0.87 | LTA4H (0.55) | LTA4HESR1ESR2MEN1KMT2A | |
| SCHEMBL9966888 | 0.87 | ESR1 (0.64) | LTA4HESR1ESR2 | |
| SCHEMBL9942716 | 0.87 | LTA4H (0.55) | LTA4HDRD3HRH3OPRK1GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |