Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267632 | 0.89 | LPAR3 (0.38) | KDM4EL3MBTL1ALDH1A1KMT2ASCN8A | |
| SCHEMBL16213529 | 0.79 | MAPT (0.39) | KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL15763372 | 0.78 | KDM4E (0.53) | KDM4EL3MBTL1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5320829 | 0.77 | SCN8A (0.36) | L3MBTL1KMT2ASCN8ASMN1; SMN2CES2 | |
| SCHEMBL24096249 | 0.74 | TAAR1 (0.48) | KDM4ESCN8ASMN1; SMN2CES2CES1 | |
| SCHEMBL10457903 | 0.74 | SCN8A (0.37) | L3MBTL1KMT2ASCN8ASMN1; SMN2CES2 | |
| SCHEMBL3267322 | 0.72 | ALDH1A1 (0.46) | KDM4EL3MBTL1ALDH1A1KMT2ASCN8A | |
| SCHEMBL15295193 | 0.72 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1KMT2ASCN8ASMN1; SMN2 | |
| SCHEMBL3119777 | 0.72 | SCN8A (0.36) | L3MBTL1KMT2ASCN8ASMN1; SMN2CES2 | |
| Hydrochloric Acid SCHEMBL7484053 | 0.72 | KDM4E (0.52) | KDM4ESCN8ASMN1; SMN2KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651219-A2 | FUNGICIDAL AZOCYCLIC AMIDES | E.I. Du Pont De Nemours And Company (US) | 2013-10-23 | — | — | EP | disclosed |
| US-20130261154-A1 | FUNGICIDAL AZOCYCLIC AMIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| WO-2012082580-A2 | FUNGICIDAL AZOCYCLIC AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261154-A1 | FUNGICIDAL AZOCYCLIC AMIDES | CYP51A1, Q6ZSR9, NOX1 | KDM4E 399/4885L3MBTL1 3936/4885ALDH1A1 1346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.