Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 7/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21820978 | 0.80 | LIPE (0.33) | LIPELPLLIPG | |
| SCHEMBL9940965 | 0.78 | LIPE (0.31) | LIPEIDO1TDO2LPLLIPG | |
| SCHEMBL16884162 | 0.77 | LPL (0.33) | LIPEJAK2BTKIDO1TDO2 | |
| SCHEMBL21821014 | 0.76 | IRAK4 (0.32) | LIPELPLLIPG | |
| SCHEMBL30387520 | 0.76 | IRAK4 (0.32) | LIPELPLLIPG | |
| SCHEMBL25596649 | 0.76 | BRD4 (0.41) | LIPEIDO1TDO2 | |
| SCHEMBL21820843 | 0.76 | LIPE (0.33) | LIPELPLLIPG | |
| SCHEMBL21820851 | 0.75 | LPL (0.33) | LIPELPLLIPG | |
| SCHEMBL24710404 | 0.75 | CCND1 (0.35) | LPLLIPG | |
| SCHEMBL21821115 | 0.74 | IRAK4 (0.32) | LIPELPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651940-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Incorporated (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012083117-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-06-21 | — | — | WO | disclosed |