Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 13/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14233866 | 1.00 | PTGES (0.42) | PTGESDPP4DPP7HPGDSSCN10A | |
| SCHEMBL9899704 | 0.94 | PTGES (0.41) | PTGESDPP4DPP7SCN10ACD38 | |
| SCHEMBL9899702 | 0.94 | PTGES (0.41) | PTGESDPP4DPP7SCN10ACD38 | |
| SCHEMBL16882989 | 0.94 | PTGES (0.41) | PTGESDPP4DPP7SCN10ACD38 | |
| SCHEMBL14234258 | 0.88 | PTGES (0.42) | PTGESDPP4DPP7HPGDS | |
| SCHEMBL9942024 | 0.88 | PTGES (0.42) | PTGESDPP4DPP7HPGDS | |
| SCHEMBL14211261 | 0.88 | RAB9A (0.41) | DPP4DPP7 | |
| SCHEMBL14233420 | 0.87 | PTGES (0.41) | PTGESCD38 | |
| SCHEMBL9942022 | 0.87 | PTGES (0.41) | PTGESCD38 | |
| SCHEMBL9941976 | 0.83 | PTGES (0.44) | PTGESDPP4DPP7HPGDSSCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076674-A1 | IMIDAZO(4,5-B)PYRIDINE-6-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |