Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9942184 | 0.83 | SLC6A3 (0.64) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL10694530 | 0.81 | SLC6A3 (0.49) | SLC6A3SLC6A2SLC6A4MEN1LMNA | |
| SCHEMBL1565904 | 0.81 | MEN1 (0.47) | SLC6A3SLC6A2SLC6A4MEN1LMNA | |
| SCHEMBL5736102 | 0.80 | SLC6A3 (0.52) | SLC6A3SLC6A2SLC6A4MEN1LMNA | |
| SCHEMBL9942278 | 0.79 | NPSR1 (0.44) | SLC6A3 | |
| SCHEMBL3554782 | 0.76 | SLC6A3 (0.72) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1155818 | 0.75 | FFAR2 (0.49) | SLC6A3SLC6A2SLC6A4FFAR2GAA | |
| SCHEMBL9644016 | 0.75 | FFAR2 (0.49) | SLC6A3SLC6A2SLC6A4FFAR2GAA | |
| SCHEMBL6912071 | 0.74 | FFAR2 (0.48) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL6912075 | 0.74 | FFAR2 (0.48) | SLC6A3SLC6A2SLC6A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076466-A2 | SUBSTITUTED 1-BENZYLCYCLOALKYLCARBOXLIC ACIDS AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-14 | — | — | WO | disclosed |