Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.44 |
| ▸ | TEC | P42680 | 1/20 | 0.40 |
| ▸ | TXK | P42681 | 1/20 | 0.40 |
| ▸ | BMX | P51813 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965016 | 0.79 | BTK (0.49) | BTKTECTXKBMXJAK3 | |
| SCHEMBL9965010 | 0.72 | BTK (0.65) | BTK | |
| SCHEMBL9939129 | 0.68 | ADRA2A (0.40) | BTKTECTXKBMXJAK3 | |
| SCHEMBL16382696 | 0.68 | BTK (0.55) | BTK | |
| SCHEMBL9965007 | 0.68 | GAA (0.44) | BTKTECTXKBMXJAK3 | |
| SCHEMBL9935615 | 0.67 | BTK (0.39) | BTK | |
| SCHEMBL16337006 | 0.65 | BTK (0.76) | BTK | |
| SCHEMBL29709510 | 0.65 | BTK (0.76) | BTK | |
| SCHEMBL9942461 | 0.65 | BTK (0.40) | BTK | |
| SCHEMBL16335770 | 0.65 | BTK (0.72) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651889-A1 | 4-AMINOINDOLE DERIVATIVES AND USE THEREOF FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'Oréal (FR) | 2013-10-23 | — | — | EP | claimed |
| EP-2651516-A2 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'Oréal (FR) | 2013-10-23 | — | — | EP | claimed |
| WO-2012080288-A1 | 4-AMINOINDOLE DERIVATIVES AND USE THEREOF FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2012-06-21 | — | — | WO | claimed |
| WO-2012080321-A2 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | claimed |