Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936909 | 0.82 | CYP1A2 (0.37) | BTKJAK2 | |
| SCHEMBL9936563 | 0.78 | BTK (0.49) | BTKAURKATPX2KEAP1 | |
| SCHEMBL9965010 | 0.72 | BTK (0.65) | BTK | |
| SCHEMBL2768819 | 0.72 | KEAP1 (0.49) | BTKAURKATPX2ADRA2ACLCN2 | |
| SCHEMBL2595142 | 0.69 | AURKA (0.46) | AURKATPX2ADRA2ACLCN2KEAP1 | |
| SCHEMBL6192602 | 0.68 | TDP1 (0.38) | BTK | |
| SCHEMBL9939129 | 0.68 | ADRA2A (0.40) | BTKADRA2ACLCN2 | |
| SCHEMBL16382696 | 0.68 | BTK (0.55) | BTK | |
| SCHEMBL9942462 | 0.67 | BTK (0.44) | BTK | |
| SCHEMBL2424952 | 0.66 | BTK (0.56) | BTKKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651516-A2 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'Oréal (FR) | 2013-10-23 | — | — | EP | claimed |
| WO-2012080285-A2 | DYE COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | claimed |
| WO-2012080321-A2 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | claimed |
| EP-2651386-A2 | DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER | L'Oréal (FR) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080289-A2 | DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |