Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.37 |
| ▸ | MEN1 | O00255 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4B | O94953 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1763428 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL8675692 | 0.76 | CYP1A2 (0.56) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL14909413 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL14910448 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL18983611 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL14909409 | 0.71 | ALDH1A1 (0.43) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL3580195 | 0.70 | ALDH1A1 (0.40) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL13314707 | 0.69 | L3MBTL1 (0.40) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL13310611 | 0.69 | ALDH1A1 (0.52) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL30888284 | 0.69 | ALDH1A1 (0.52) | ALDH1A1MEN1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363705-B9 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2012-11-07 | — | — | EP | disclosed |
| EP-1363705-B1 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2012-06-13 | — | — | EP | disclosed |