Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 16/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9930271 | 0.86 | CCR2 (0.57) | CCR2BRAFALDH1A1GAA | |
| SCHEMBL9930855 | 0.78 | CCR2 (0.56) | CCR2BRAF | |
| SCHEMBL9931076 | 0.78 | CCR2 (0.67) | CCR2BRAFALDH1A1 | |
| SCHEMBL9931050 | 0.76 | CCR2 (0.58) | CCR2BRAFMAPTHTT | |
| SCHEMBL19415719 | 0.75 | CCR2 (0.71) | CCR2BRAFMAPTHTT | |
| SCHEMBL9930439 | 0.75 | CCR2 (0.71) | CCR2BRAFMAPTHTT | |
| SCHEMBL7592227 | 0.72 | CCR2 (0.67) | CCR2BRAF | |
| SCHEMBL9942713 | 0.72 | CCR2 (0.58) | CCR2BRAFALDH1A1MAPT | |
| SCHEMBL16747603 | 0.72 | CCR2 (0.66) | CCR2BRAFALDH1A1 | |
| SCHEMBL9968224 | 0.72 | CCR2 (0.58) | CCR2BRAFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651901-A1 | NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | Allergan, Inc. (US) | 2013-10-23 | — | — | EP | claimed |
| WO-2012082633-A1 | NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-21 | — | — | WO | claimed |