Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990955 | 0.89 | MEN1 (0.35) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL1979291 | 0.87 | MEN1 (0.40) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL9935932 | 0.85 | MEN1 (0.33) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL9936903 | 0.83 | MEN1 (0.36) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL1987433 | 0.71 | — | — | |
| SCHEMBL1983039 | 0.70 | MEN1 (0.30) | MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL9940493 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL1989198 | 0.68 | — | — | |
| SCHEMBL15545409 | 0.67 | SMN1; SMN2 (0.37) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL15127630 | 0.67 | ALDH1A1 (0.42) | MEN1MAPTHTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080286-A9 | DYEING COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A CATIONIC 3,5-DIAMINOPYRIDINE COUPLER | L'OREAL (FR) | 2013-01-31 | — | — | WO | claimed |
| WO-2012080286-A2 | DYEING COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A CATIONIC 3,5-DIAMINOPYRIDINE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | claimed |