Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 16/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9930307 | 0.87 | CCR2 (0.66) | CCR2PKMBRAF | |
| SCHEMBL9942713 | 0.80 | CCR2 (0.58) | CCR2BRAFALDH1A1 | |
| SCHEMBL9930914 | 0.78 | CCR2 (0.77) | CCR2PKMBRAF | |
| SCHEMBL9930749 | 0.78 | CCR2 (1.00) | CCR2PKMBRAF | |
| SCHEMBL16747585 | 0.77 | CCR2 (0.70) | CCR2PKM | |
| SCHEMBL9930526 | 0.76 | CCR2 (0.81) | CCR2PKMBRAF | |
| SCHEMBL9930895 | 0.76 | CCR2 (0.80) | CCR2PKMBRAF | |
| SCHEMBL9930745 | 0.76 | CCR2 (0.81) | CCR2PKMBRAF | |
| SCHEMBL9931481 | 0.76 | CCR2 (0.77) | CCR2PKMBRAF | |
| SCHEMBL9930558 | 0.76 | CCR2 (0.77) | CCR2PKMBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651901-A1 | NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | Allergan, Inc. (US) | 2013-10-23 | — | — | EP | claimed |
| WO-2012082633-A1 | NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-21 | — | — | WO | claimed |