Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.54 |
| ▸ | PGR | P06401 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL835852 | 0.81 | NR3C1 (0.81) | NR3C1PGR | |
| SCHEMBL834373 | 0.73 | NR3C1 (0.82) | NR3C1PGR | |
| SCHEMBL9943361 | 0.72 | NR3C1 (0.62) | NR3C1PGR | |
| SCHEMBL9943362 | 0.72 | NR3C1 (0.62) | NR3C1PGR | |
| SCHEMBL835893 | 0.72 | NR3C1 (0.81) | NR3C1PGR | |
| SCHEMBL850993 | 0.72 | NR3C1 (0.81) | NR3C1PGR | |
| SCHEMBL836629 | 0.71 | NR3C1 (0.82) | NR3C1PGR | |
| SCHEMBL836628 | 0.71 | NR3C1 (0.82) | NR3C1PGR | |
| SCHEMBL851077 | 0.70 | NR3C1 (0.91) | NR3C1PGR | |
| SCHEMBL835459 | 0.70 | NR3C1 (0.91) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102169-B1 | INDAZOLYL AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | ASTRAZENECA AB (SE) | 2012-06-20 | — | — | EP | claimed |