Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227086 | 1.00 | CYP2D6 (0.66) | CYP2D6CYP3A4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3023682 | 1.00 | CYP2D6 (0.66) | CYP2D6CYP3A4ALDH1A1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL5266699 | 0.98 | CYP2D6 (0.64) | CYP2D6CYP3A4ALDH1A1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL5266695 | 0.98 | CYP2D6 (0.64) | CYP2D6CYP3A4ALDH1A1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL16333750 | 0.98 | CYP2D6 (0.64) | CYP2D6CYP3A4ALDH1A1CYP1A2CYP2C19 | |
| Methane SCHEMBL692994 | 0.98 | CYP2D6 (0.64) | CYP2D6CYP3A4ALDH1A1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL4221752 | 0.98 | CYP2D6 (0.64) | CYP2D6CYP3A4ALDH1A1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL16333749 | 0.98 | CYP2D6 (0.64) | CYP2D6CYP3A4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL556001 | 0.95 | CYP2D6 (0.59) | CYP2D6CYP3A4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3459933 | 0.95 | CYP2D6 (0.59) | CYP2D6CYP3A4ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111363732-B | Transaminase mutant from aspergillus terreus NIH2624 and application thereof | 卡柔恩赛生物技术湖北有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-116042560-A | Mutant of recombinant aminotransferase and application thereof | 清华大学 | 2023-05-02 | — | — | CN | claimed |
| CN-111718250-B | Method for preparing R-citronellal | 万华化学集团股份有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-110950840-B | Preparation method of trelagliptin succinate | 江苏天和制药有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-111718250-A | Method for preparing R-citronellal | 万华化学集团股份有限公司 | 2020-09-29 | — | — | CN | claimed |
| CN-111363732-A | Transaminase mutant derived from aspergillus terreus NIH2624 and application thereof | 重庆迪维斯生物科技有限公司 | 2020-07-03 | — | — | CN | claimed |
| CN-110950840-A | Preparation method of trelagliptin succinate | 江苏天和制药有限公司 | 2020-04-03 | — | — | CN | claimed |
| EP-2623593-B1 | NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE | KANEKA CORP (JP) | 2017-07-12 | — | — | EP | claimed |
| EP-2684953-B1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | KANEKA CORP (JP) | 2017-06-28 | — | — | EP | claimed |
| EP-2623595-B1 | NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF | KANEKA CORP (JP) | 2016-11-02 | — | — | EP | claimed |
| CN-103534353-A | Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same | KANEKA CORP | 2014-01-22 | — | — | CN | claimed |
| EP-2684953-A1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | Kaneka Corporation (JP) | 2014-01-15 | — | — | EP | claimed |
| US-20140004575-A1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | KANEKA CORPORATION (JP) | 2014-01-02 | — | — | US | claimed |
| US-20130210092-A1 | Novel Transaminase, Gene Encoding the Same, and Method Using Them | KANEKA CORPORATION (JP) | 2013-08-15 | — | — | US | claimed |
| EP-2623593-A1 | NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE | Kaneka Corporation (JP) | 2013-08-07 | — | — | EP | claimed |
| EP-2623595-A1 | NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF | Kaneka Corporation (JP) | 2013-08-07 | — | — | EP | claimed |
| US-20130196389-A1 | NOVEL TRANSAMINASE EXHIBITING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR USING THEM | KANEKA CORPORATION (JP) | 2013-08-01 | — | — | US | claimed |
| CN-103140580-A | Novel aminotransferase, gene encoding the same, and method for using the same | KANEKA CORP | 2013-06-05 | — | — | CN | claimed |
| US-20060270847-A1 | Process for producing nitrogenous heterocyclic compound | TORAY FINE CHEMICALS CO., LTD. (JP) | 2006-11-30 | — | — | US | claimed |
| EP-1640364-A1 | PROCESS FOR PRODUCING NITROGENOUS HETEROCYCLIC COMPOUND | Toray Fine Chemicals Co., Ltd. (JP) | 2006-03-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270847-A1 | Process for producing nitrogenous heterocyclic compound | HNMT, HRH4, QDPR | CYP2D6 745/4885CYP3A4 153/4885ALDH1A1 2724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.