Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.67 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708449 | 0.98 | HRH3 (0.63) | HRH3HRH4ALDH1A1KDM4EHDAC1 | |
| Hydrochloric Acid SCHEMBL3715506 | 0.96 | HRH3 (0.61) | HRH3HRH4ALDH1A1KDM4EHDAC1 | |
| SCHEMBL3693072 | 0.86 | HRH3 (0.62) | HRH3HRH4ALDH1A1KDM4EHDAC1 | |
| SCHEMBL8510915 | 0.84 | ITGB3 (0.56) | HRH3ALDH1A1KDM4EHDAC1CYP2D6 | |
| SCHEMBL8745021 | 0.84 | SIGMAR1 (0.65) | HRH3ALDH1A1KDM4EITGB3ITGA2B | |
| SCHEMBL5304957 | 0.82 | MC4R (0.62) | HRH3ALDH1A1KDM4EHDAC6ITGB3 | |
| SCHEMBL5477508 | 0.82 | SMN1; SMN2 (0.63) | HRH3ALDH1A1KDM4EITGB3ITGA2B | |
| SCHEMBL8745033 | 0.82 | ITGB3 (0.55) | HRH3ALDH1A1KDM4EHDAC1ITGB3 | |
| SCHEMBL4277270 | 0.82 | HRH3 (1.00) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL6223200 | 0.81 | HRH3 (0.61) | HRH3HRH4ALDH1A1KDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006232-B2 | Pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-04-14 | — | — | US | disclosed |
| US-20120208797-A1 | PYRIMIDONE DERIVATIVES | SANOFI (FR) | 2012-08-16 | — | — | US | disclosed |
| EP-2464632-A1 | PYRIMIDONE DERIVATIVES USED AS TAU PROTEIN KINASE 1 INHIBITORS | Mitsubishi Tanabe Pharma Corporation (JP) | 2012-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208797-A1 | PYRIMIDONE DERIVATIVES | PSEN1, PRNP, PSEN2 | HRH3 662/4885HRH4 1519/4885ALDH1A1 2075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.