Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 2/20 | 0.55 |
| ▸ | G6PD | P11413 | 2/20 | 0.55 |
| ▸ | MC4R | P32245 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CCR6 | P51684 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9945018 | 0.88 | ALDH1A1 (0.42) | ALDH1A1LMNAPKML3MBTL1ITGA4 | |
| SCHEMBL9898727 | 0.87 | PTGES (0.49) | ALDH1A1LMNAPKML3MBTL1ITGA4 | |
| SCHEMBL9944983 | 0.86 | ALDH1A1 (0.58) | ALDH1A1LMNAPKML3MBTL1ITGA4 | |
| SCHEMBL9945038 | 0.86 | ALDH1A1 (0.52) | ALDH1A1LMNAPKML3MBTL1ITGA4 | |
| SCHEMBL9944805 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LMNAPKML3MBTL1ITGA4 | |
| SCHEMBL9946643 | 0.75 | PTGES (0.49) | LMNATP53MAPT | |
| SCHEMBL9945036 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNAPKML3MBTL1ITGA4 | |
| SCHEMBL9946856 | 0.74 | MAPT (0.53) | ALDH1A1LMNAPKML3MBTL1ITGA4 | |
| SCHEMBL9946779 | 0.74 | MAPT (0.49) | ALDH1A1PKMKDM4EMAPK1MAPT | |
| SCHEMBL9898485 | 0.74 | PTGES (0.47) | ALDH1A1LMNAPKMPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149676-A1 | NOVEL COMPOUNDS | PTGS1, PTGER1, PTGES | ALDH1A1 126/4885LMNA 1817/4885PKM 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.