SCHEMBL994483

SCHEMBL994483

CC1(C)CCCC(C)(C)N1CCC(CCCCCCCC(=O)O)(CCN1C(C)(C)CCCC1(C)C)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.33
NFKB1 P19838 2/20 0.33
LMNA P02545 1/20 0.33
PMP22 Q01453 1/20 0.33
CYP2C19 P33261 1/20 0.33
TBXAS1 P24557 2/20 0.33
GPR84 Q9NQS5 7/20 0.33
PPARG P37231 7/20 0.33
PPARD Q03181 7/20 0.33
PPARA Q07869 7/20 0.33
HDAC11 Q96DB2 5/20 0.33
PTPN1 P18031 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TLR2 O60603 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
FABP4 P15090 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
SLC22A8 Q8TCC7 1/20 0.33
MEN1 O00255 1/20 0.33
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11202985 0.94 TSHR (0.35) TSHRNFKB1CYP2C19
SCHEMBL4453278 0.82 TSHR (0.43) TSHRNFKB1LMNAPMP22CYP2C19
SCHEMBL11807005 0.81 TSHR (0.38) TSHRNFKB1CYP2C19
Sebacic Acid SCHEMBL28583209 0.79 GPR84 (0.44) TSHRNFKB1LMNAPMP22CYP2C19
SCHEMBL561947 0.78 TSHR (0.36) TSHRNFKB1LMNAPMP22CYP2C19
SCHEMBL10756490 0.77
Sebacic Acid SCHEMBL8958570 0.75 TSHR (0.56) TSHRNFKB1LMNAPMP22CYP2C19
SCHEMBL9054086 0.74 TDP1 (0.33) TSHRNFKB1LMNAPMP22TBXAS1
SCHEMBL699481 0.72 TSHR (0.36) TSHRNFKB1LMNAPMP22TBXAS1
SCHEMBL11809146 0.72 FOLH1 (0.42) TSHRNFKB1LMNAPMP22CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0096297-A2 Process for the preparation of 1-sulfo-2-oxoazetidine derivatives F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1983-12-21 EP claimed
EP-2413697-B1 STABILISATION OF COMPOUNDS CONTAINING IODINE LANXESS DEUTSCHLAND GMBH (DE) 2017-11-08 EP disclosed
EP-2779830-B1 STABILIZATION OF COMPOUNDS CONTAINING IODINE HAVING POLYMERS COMPRISING NITROGEN LANXESS DEUTSCHLAND GMBH (DE) 2017-05-17 EP disclosed
US-9585384-B2 Stabilization of compounds comprising iodine LANXESS DEUTSCHLAND GMBH (DE) 2017-03-07 US disclosed
US-9328065-B2 Nitrogen-containing inorganic carrier materials LANXESS DEUTSCHLAND GMBH (DE) 2016-05-03 US disclosed
US-9326502-B2 Stabilization of compounds containing iodine having polymers comprising nitrogen LANXESS DEUTSCHLAND GMBH (DE) 2016-05-03 US disclosed
US-9296878-B2 Fungicide formulations for plasticized PVC LANXESS DEUTSCHLAND GMBH (DE) 2016-03-29 US disclosed
EP-2831160-B1 STABLE COMPOSITIONS OF THIABENDAZOLE AND IODINE-CONTAINING FUNGICIDES LANXESS DEUTSCHLAND GMBH (DE) 2016-03-23 EP disclosed
EP-2831161-B1 FUNGICIDE FORMULATIONS FOR PLASTICIZED PVC LANXESS DEUTSCHLAND GMBH (DE) 2015-11-18 EP disclosed
US-20150203660-A1 FUNGICIDE FORMULATIONS FOR PLASTICIZED PVC LANXESS DEUTSCHLAND GMBH (DE) 2015-07-23 US disclosed
US-4426471-A TETRAALKYLPIPERIDINES CIBA-GEIGY CORPORATION (US) 1984-01-17 US disclosed
EP-0002753-B1 STABILISATION OF HEAT-CURABLE METALLIC ENAMEL PAINTS AGAINST THE ACTION OF LIGHT, HUMIDITY AND OXYGEN BY THE ADDITION OF POLYALKYLPIPERIDINE DERIVATIVES CIBA-GEIGY AG (CH) 1983-10-05 EP disclosed
EP-0016723-B1 LIGHT STABILISATION OF TWO-LAYER COMPOSITE LACQUERS CIBA-GEIGY AG (CH) 1983-06-01 EP disclosed
EP-0006213-B1 LIGHT STABILIZATION OF ACID CATALYSED STOVING ENAMELS CIBA-GEIGY AG (CH) 1982-09-01 EP disclosed
US-4344876-A N-SUBSTITUTED 2,2,6,6-TETRAALYKYL PIPERIDINE PHOTOSTABILIZERS CIBA-GEIGY CORPORATION (US) 1982-08-17 US disclosed
US-4315848-A PROTECTIVE COATING FOR AUTOMOBILES CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4278589-A 2-[2-Hydroxy-3,5-di-(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole and stabilized compositions CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
US-4278590-A AUTOMOBILE FINISHES CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
EP-0016723-A1 Light stabilisation of two-layer composite lacquers CIBA-GEIGY AG (CH) 1980-10-01 EP disclosed
EP-0006213-A1 Light stabilization of acid catalysed stoving enamels CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed