Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 3/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.35 |
| ▸ | TUBB | P07437 | 3/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16687399 | 0.90 | ALDH1A1 (0.48) | ALDH1A1MAPK1MAPTHPGDPRKDC | |
| SCHEMBL2588646 | 0.80 | MAPT (0.55) | ALDH1A1MAPK1MAPTHPGDPRKDC | |
| SCHEMBL31132205 | 0.76 | TPMT (0.54) | ALDH1A1MAPK1MAPTHPGDPRKDC | |
| SCHEMBL2807788 | 0.76 | TPMT (0.54) | ALDH1A1MAPK1MAPTHPGDPRKDC | |
| SCHEMBL12552993 | 0.74 | SRC (0.49) | ALDH1A1MAPK1MAPTHPGDPRKDC | |
| SCHEMBL524712 | 0.74 | ALDH1A1 (0.63) | ALDH1A1MAPK1MAPTHPGDPRKDC | |
| SCHEMBL30122857 | 0.74 | ALDH1A1 (0.63) | ALDH1A1MAPK1MAPTHPGDPRKDC | |
| SCHEMBL17221862 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MAPK1MAPTHPGDPRKDC | |
| SCHEMBL14958356 | 0.73 | ALDH1A1 (0.61) | ALDH1A1MAPK1MAPTHPGDPRKDC | |
| SCHEMBL31063093 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPK1MAPTHPGDPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | ALDH1A1 4010/4885MAPK1 2307/4885MAPT 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.