Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | MB | P02144 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | RARG | P13631 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9162 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL861674 | 0.82 | SMN1; SMN2 (0.84) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL9945928 | 0.77 | ALDH1A1 (0.58) | SMN1; SMN2L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL2615418 | 0.76 | KMT2A (0.81) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL1753885 | 0.76 | KMT2A (0.81) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL3818831 | 0.75 | SMN1; SMN2 (1.00) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL11158565 | 0.75 | MAPT (0.83) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL9946011 | 0.74 | CYP17A1 (0.49) | SMN1; SMN2CA12CA1CA9NAMPT | |
| SCHEMBL15481258 | 0.74 | DEGS1 (0.57) | SMN1; SMN2KMT2AMEN1TDP1RAB9A | |
| Acetaminophen SCHEMBL5211993 | 0.74 | SMN1; SMN2 (0.64) | SMN1; SMN2L3MBTL1HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | SMN1; SMN2 3273/4885L3MBTL1 4393/4885HTT 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.