SCHEMBL9945928

SCHEMBL9945928

CB(O)c1cccc(NC(C)=O)c1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
HSD17B10 Q99714 3/20 0.58
CYP1A2 P05177 1/20 0.58
RAB9A P51151 3/20 0.53
POLB P06746 1/20 0.53
NR4A1 P22736 1/20 0.53
NAPRT Q6XQN6 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
TSHR P16473 2/20 0.49
TP53 P04637 2/20 0.49
NQO2 P16083 1/20 0.47
MAPT P10636 1/20 0.47
NPC1 O15118 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8930 0.87 ALDH1A1 (0.59) ALDH1A1HSD17B10CYP1A2RAB9APOLB
SCHEMBL18100124 0.83 SMN1; SMN2 (0.62) ALDH1A1HSD17B10CYP1A2RAB9APOLB
SCHEMBL1901172 0.80 ALDH1A1 (0.76) ALDH1A1HSD17B10CYP1A2RAB9APOLB
SCHEMBL18100115 0.80 TGM2 (0.58)
SCHEMBL9946007 0.78 HDAC3 (0.47)
SCHEMBL9945929 0.77 SMN1; SMN2 (0.59) ALDH1A1HSD17B10RAB9APOLBNAPRT
SCHEMBL2556313 0.77 MAPT (0.62) ALDH1A1HSD17B10CYP1A2RAB9APOLB
SCHEMBL20221426 0.76 ALDH1A1 (0.46) ALDH1A1CYP1A2RAB9APOLBSMN1; SMN2
SCHEMBL1015209 0.75 ALDH1A1 (0.45) ALDH1A1HSD17B10CYP1A2RAB9APOLB
SCHEMBL7023178 0.74 ALDH1A1 (0.61) ALDH1A1HSD17B10CYP1A2RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9480166-B2 Method of manufacturing non-firing type electrode E I DU PONT DE NEMOURS AND COMPANY (US) 2016-10-25 US disclosed
US-20140306165-A1 METHOD OF MANUFACTURING NON-FIRING TYPE ELECTRODE E I DU PONT DE NEMOURS AND COMPANY (US) 2014-10-16 US disclosed
US-20120149693-A1 THERAPEUTIC COMPOUNDS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149693-A1 THERAPEUTIC COMPOUNDS HTR2C, GRK2, GRK3 ALDH1A1 4010/4885HSD17B10 3109/4885CYP1A2 2891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.